Integrating genomics, development and evolution to elucidate the genotype-phenotype map of Drosophila wing morphology

我的长期研究目标是了解自然表型变异的遗传、基因组和发育基础。具体来说，为表型变化的精确和长期预测提供更广泛的定量遗传学框架的目标，迫切需要对遗传和环境变异如何调节发育有更全面和详细的了解。我的实验室致力于解决关于野生型遗传背景下自然遗传变异功能的关键问题，以及这最终如何形成表型效应。我们的工作是利用遗传模式生物(

My long term research goal is to understand the genetic, genomic and developmental basis of natural phenotypic variation. Specifically, the goal of providing a broader quantitative genetics framework for precise and long-term predictions of phenotypic change critically requires a more integrative and detailed understanding of how genetic and environmental variation modulates development. Research in my lab works to address critical issues regarding the function of natural genetic variants across wild type genetic backgrounds, and how this ultimately shapes phenotypic effects. Our work is at the interface of developmental and quantitative genomics using a genetic model organism (