课题基金 / 基金详情

Investigating drug therapies for inherited and acquired long QT syndrome using iPSC-derived cardiomyocytes and zebrafish whole hearts as translational models

Investigating drug therapies for inherited and acquired long QT syndrome using iPSC-derived cardiomyocytes and zebrafish whole hearts as translational models
使用 iPSC 衍生的心肌细胞和斑马鱼全心作为转化模型研究遗传性和获得性长 QT 综合征的药物治疗
批准号：
372315
负责人：
Claydon Thomas W
金额：
$49.6万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=372315&lang=en
关键词：
Activator Drugs Crispr Genome Editing Electrophysiology Herg Potassium Channel Induced Pluripotent Stem Cells Long Qt Syndrome

项目摘要

项目成果

Claydon Thomas W的其他基金

相似基金

相关文献

中文摘要
翻译
每一次心跳都是由一个协调的电波产生的，它传播到整个心肌。每一次波动都会导致肌肉收缩，并将血液输送到循环中。浪必须被严格控制，这样心脏才能跳动
英文摘要
Each heart beat is generated by a co-ordinated wave of electrical excitation that spreads across the heart muscle. Each wave causes the muscle to contract and pump blood in the circulation. The waves have to be tightly controlled so that the heart beats i
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanism-based targeted rescue of hERG channel dysfunction in hiPSC-CMs
海外基金