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Nuclear Receptor Signaling in High-Fat Diet and Glucocorticoid-Induced Metabolic Disease

Nuclear Receptor Signaling in High-Fat Diet and Glucocorticoid-Induced Metabolic Disease
高脂饮食和糖皮质激素诱导的代谢性疾病中的核受体信号传导
批准号:
372155
负责人:
Cummins Carolyn L
金额:
$59.63万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

项目摘要

项目成果

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中文摘要
翻译
包括糖尿病和肥胖症在内的代谢性疾病在西方世界正达到流行水平。应激激素对糖皮质激素受体信号通路的慢性激活可导致糖尿病和代谢功能障碍。糖尿病是
英文摘要
Metabolic diseases, including diabetes and obesity, are reaching epidemic levels in the Western world. Chronic activation of the glucocorticoid receptor signaling pathway by stress hormones can contribute to diabetes and metabolic dysfunction. Diabetes is
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会议论文
Transcription factor interplay as a driving force in the hepatic response to fasting and its dysregulation in metabolic disease
  • 批准号:
    400664
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    Operating Grants
  • 资助金额:
    $0.0万
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Developing a Novel Therapeutic for Cushing's Syndrome
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  • 资助金额:
    $11.66万
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Defining the structural basis for LXR beta antagonism
  • 批准号:
    292671
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    $9.23万
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Molecular Determinants of Corticosteroid Actions in Glucose Metabolism
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海外基金