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Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration

Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration
驯鹿鹿茸:研究组织再生的细胞和分子机制的独特模型
批准号:
RGPIN-2017-04825
负责人:
Biernaskie, Jeffrey
金额:
$2.48万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
翻译
哺乳动物进化选择了加速伤口闭合,代价是产生纤维化瘢痕。为了使未来能够开发改善皮肤愈合的疗法,全面了解促进再生与纤维化愈合反应的分子信号将是必不可少的。我们目前对这些不同过程的理解很差,部分原因是我们缺乏一个强大的哺乳动物组织再生模型。
英文摘要
Mammalian evolution has selected for accelerated wound closure at the expense of generating fibrotic scar. To enable future development of therapies that improve skin healing, a comprehensive understanding of the molecular signals that promote a regenerative versus fibrotic healing response will be essential. Our current understanding of these divergent processes is poor, partly because we lack a robust mammalian model of tissue regeneration.
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Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration
  • 批准号:
    RGPIN-2017-04825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.95万
  • 财政年份:
    2021
  • 负责人:
    Biernaskie, Jeffrey
  • 依托单位:
Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration
  • 批准号:
    RGPIN-2017-04825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.48万
  • 财政年份:
    2020
  • 负责人:
    Biernaskie, Jeffrey
  • 依托单位:
Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration
  • 批准号:
    RGPIN-2017-04825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.48万
  • 财政年份:
    2019
  • 负责人:
    Biernaskie, Jeffrey
  • 依托单位:
Reindeer Antler Velvet: a unique model to study cellular and molecular mechanisms underlying tissue regeneration
  • 批准号:
    RGPIN-2017-04825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.48万
  • 财政年份:
    2018
  • 负责人:
    Biernaskie, Jeffrey
  • 依托单位:
海外基金