Neural responses to abiotic stress in insects

我的研究项目是关于环境因素的影响，如温度变化或氧气供应，对神经系统的运作。这项研究之所以重要，至少有两个原因。从纯粹的生物学角度来看，应对这些环境因素的能力决定了不同物种的地理范围，了解它们的生理影响可以预测全球气候变化的生态后果。从生物医学的角度来看，同样的因素也与人类病理有关，如发烧和中风引起的缺氧。在细胞水平上，像蝗虫和人类这样不同的动物的神经机制非常相似，所以我对昆虫的研究可以为其他人在哺乳动物模型中进行测试提供假设。

My research program is concerned with the impact of environmental factors, such as variable temperatures or oxygen availability, on the operation of nervous systems. This research is important for at least two reasons. From a purely biological perspective, the ability to cope with these environmental factors determines the geographical ranges of different species and understanding their physiological effects allows predictions about the ecological consequences of global climate change. From a biomedical perspective, the same factors are associated with human pathology such as fever, and oxygen deprivation resulting from a stroke. At a cellular level, neural mechanisms are remarkably similar in animals as diverse as locusts and humans, so my research with insects can generate hypotheses for others to test in mammalian models.