The Role of Respiratory Chemoreflexes at Work, Rest and Play

几十年来，现代生物学研究已经在越来越微观的尺度上取得了进展，其中理解细胞、分子和遗传机制一直是主导主题。尽管在理解基本细胞机制方面有了重要的新发现，但在理解身体功能方面，这种基因组观点的预测性比预期的要低，令人惊讶的是，几乎没有医学上的进展。专注于理解器官系统的功能和相互关系的综合生理学家，现在重新占据了追求理解生物功能的中心舞台。一个重要的生物学功能仍然需要综合生理学家的研究努力是呼吸的控制。

For decades, modern biological research has progressed down an increasingly microscopic scale, where understanding cellular, molecular and genetic mechanisms has been the dominant theme. Although important new discoveries toward understanding basic cellular mechanisms have resulted, this genomic perspective has been less predictive than anticipated on understanding body function, and surprisingly few medical advances have resulted. Integrative physiologists, who focus on understanding the functions of and relationships between organ systems, are now re-taking center stage in the pursuit of understanding biological function. One important biological function that still requires the research efforts of integrative physiologists is the control of breathing.