Computer simulations of lipids
Computer simulations of lipids
批准号:
RGPIN-2015-05305
负责人:
Tieleman, Peter
金额:
$6.48万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
生物分子,如蛋白质、DNA、脂类和碳水化合物,存在于微观宇宙中,时间和长度尺度比我们测量长度和时间的米和秒小6-12个数量级。它们在纳秒的时间尺度上快速移动,并与只有十分之几纳米大小的单个水分子相互作用。与可见光的波长相比,大多数生物分子都非常小。这意味着它们不能用普通显微镜看到,尽管有许多复杂的实验方法来测量生物分子的行为、形状和相互作用的各个方面。对于这样的实验,计算机模拟是一种互补的方法,既可以单独进行,也可以直接与无法在分子水平上解释的实验相结合。
英文摘要
Biomolecules, such as proteins, DNA, lipids, and carbohydrates, exist in a microscopic universe with time and length scales 6-12 orders of magnitude smaller than the meters and seconds in which we measure length and time. They move rapidly on a time scale of nanoseconds and interact with individual water molecules the size of a few tenths of a nanometer. Most biomolecules are very small compared to the wavelength of visible light. This means they cannot be seen with ordinary microscopes, although there are many sophisticated experimental methods to measure aspects of the behaviour, shape, and interactions of biomolecules. Computer modeling is a complimentary approach to such experiments, both by themselves and in direct combination with experiments that otherwise could not be interpreted at a molecular level.
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Computer simulations of lipids
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批准号:RGPIN-2020-04209
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项目类别:Discovery Grants Program - Individual
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资助金额:$7.65万
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财政年份:2022
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2022
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2020-04209
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项目类别:Discovery Grants Program - Individual
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资助金额:$7.65万
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财政年份:2021
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2021
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2020
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2020-04209
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项目类别:Discovery Grants Program - Individual
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资助金额:$7.65万
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财政年份:2020
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2019
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2015-05305
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.48万
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财政年份:2019
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2015-05305
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.48万
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财政年份:2018
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2018
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负责人:Tieleman, Peter
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依托单位:
Molecular Simulation
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批准号:CRC-2016-00271
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项目类别:Canada Research Chairs
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资助金额:$10.93万
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财政年份:2017
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负责人:Tieleman, Peter
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依托单位:
High performance network and storage fabric for a GPU cluster
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批准号:RTI-2017-00018
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项目类别:Research Tools and Instruments
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资助金额:$10.93万
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财政年份:2017
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2015-05305
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.48万
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财政年份:2016
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负责人:Tieleman, Peter
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依托单位:
Development of the next generation of lipid nanoparticles for gene therapy
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批准号:463247-2014
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项目类别:Strategic Projects - Group
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资助金额:$9.29万
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财政年份:2016
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:RGPIN-2015-05305
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.48万
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财政年份:2015
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负责人:Tieleman, Peter
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依托单位:
Development of the next generation of lipid nanoparticles for gene therapy
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批准号:463247-2014
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项目类别:Strategic Projects - Group
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资助金额:$9.29万
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财政年份:2015
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:238357-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.56万
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财政年份:2014
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负责人:Tieleman, Peter
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依托单位:
Development of the next generation of lipid nanoparticles for gene therapy
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批准号:463247-2014
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项目类别:Strategic Projects - Group
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资助金额:$11.4万
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财政年份:2014
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:238357-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.56万
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财政年份:2013
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负责人:Tieleman, Peter
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依托单位:
Computer simulations of lipids
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批准号:238357-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.56万
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财政年份:2012
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负责人:Tieleman, Peter
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依托单位:
国内基金
海外基金
Galaxy Analytical Modeling
Evolution (GAME) and cosmological
hydrodynamic simulations.
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批准号:
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项目类别:省市级项目
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资助金额:10.0万元
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批准年份:2025
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负责人:Antonios Katsianis
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依托单位: