Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
批准号:
RGPIN-2017-06683
负责人:
Wilds, Christopher
金额:
$3.28万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
脱氧核糖核酸(DNA)和核糖核酸(RNA)是生命的中心分子。60多年前,沃森和克里克描述了DNA双螺旋结构的发现,这一发现继续推动着生物学和医学的许多进步。最近,这种优雅的结构及其特定相互作用的性质启发了科学家和工程师研究核酸的技术应用。通过有机合成,可以实现对核酸支架的修饰,从而获得具有更多官能度的分子,用于广泛的应用,从而改善我们的社会。
英文摘要
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are the central molecules of life. The discovery of the double helix structure of DNA, described by Watson and Crick over 60 years ago, continues to lead to numerous advances in biology and medicine. More recently, this elegant structure and the nature of its specific interactions have inspired scientists and engineers to investigate technological applications for nucleic acids. Through organic synthesis, modification of the nucleic acid scaffold can be achieved leading to molecules with increased functionality for a broad range of applications that can improve our society.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2022
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2021
-
负责人:Wilds, Christopher
-
依托单位:
Urgent Replacement of a Biomolecular Imager For Bioorganic and Biological Chemistry Research
-
批准号:RTI-2021-00470
-
项目类别:Research Tools and Instruments
-
资助金额:$10.16万
-
财政年份:2020
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2020
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2019
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2018
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2016
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2014
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2013
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2013
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2012
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2012
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2011
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2011
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2010
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and characterization of chemically modified oligonucleotides as probes of DNA repair processes.
-
批准号:299384-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2010
-
负责人:Wilds, Christopher
-
依托单位:
use of novel interstrand cross-linked DNA duplexes to investigate resistance to bifunctional alkylating chemotherapeutic agents
-
批准号:299384-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2009
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2009
-
负责人:Wilds, Christopher
-
依托单位:
Canada Research in Biological Chemistry
-
批准号:1000202062-2003
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2008
-
负责人:Wilds, Christopher
-
依托单位:
use of novel interstrand cross-linked DNA duplexes to investigate resistance to bifunctional alkylating chemotherapeutic agents
-
批准号:299384-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2008
-
负责人:Wilds, Christopher
-
依托单位:
国内基金
海外基金
基于Zip Nucleic Acids引物对高度降解和低拷贝DNA检材的STR分型研究
-
批准号:81072511
-
项目类别:面上项目
-
资助金额:31.0万元
-
批准年份:2010
-
负责人:严江伟
-
依托单位:
肽核酸(Peptide Nucleic Acid - PNA)电化学生物传感器的研究
-
批准号:20703006
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2007
-
负责人:李晓宏
-
依托单位: