The timing of nutrient uptake in the Chinook salmon intestine.

加拿大是不断增长的水产养殖业的领导者，这为我们的经济增加了30亿美元(加拿大水产养殖业联盟)。鲑鱼养殖业约占该行业的60%。尽管大西洋鲑鱼目前主导着加拿大的生产，但太平洋鲑鱼物种，如奇努克鲑鱼，由于其较高的市场价格和对疾病和寄生虫的抵抗力，对生产者越来越有吸引力。我们与黄岛水产养殖有限公司(YIAL)合作，YIAL是加拿大历史最悠久的太平洋三文鱼养殖场之一，自1985年以来一直生产优质有机奇努克三文鱼上市。YIAL面临的一个主要问题是如何优化产品数量和产品质量，同时将饲料成本降至最低，饲料成本是鲑鱼养殖场运营成本的主要组成部分。像所有动物一样，鱼有天生的24小时周期，它们在最活跃的特定时间进食和消化食物。这些日常活动的周期被称为昼夜节律，这一发现得到了2017年诺贝尔生理学奖的认可。我们的实验室研究了消化道的昼夜节律，我们建议研究奇努克鲑鱼肠道的昼夜节律，以帮助YIAL优化鲑鱼产量。为此，我们将首先测试不同品系和阶段的奇努克鲑鱼的消化活性，以找出一天中什么时间消化最高，以及哪些种群的消化效率最高。这些试验将使饲料和存栏量与养分吸收的最佳时间保持一致，从而降低饲料成本和浪费。我们的项目将专门为YIAL的利益而关注中国三文鱼，然而，我们的工作将很容易转移到加拿大的许多其他水产养殖生产者。

Canada is a leader in a growing aquaculture industry, that adds over $3 billion to our economy (CanadianAquaculture Industry Alliance). Salmon aquaculture claims ~60% of this industry. Although Atlantic salmoncurrently dominates Canadian production, Pacific salmon species such as Chinook salmon are increasinglyattractive to producers given their higher market price, and resistance to diseases and parasites. We arepartnering with Yellow Island Aquaculture Limited (YIAL), one of Canada's oldest Pacific salmon farms thathas produced premium organic Chinook salmon for market since 1985. A major question for YIAL, is how tooptimize product quantity and product quality while minimizing feed costs, a primary component of salmonfarm operating costs. Fish, like all animal species, possess innate 24 hour cycles, and they feed and digest foodat specific times when they are most active. These cycles of daily activity are called Circadian Rhythms, a topicwhose discovery was recognized by the Nobel Prize in Physiology, 2017. Our lab studies the circadian rhythmsof the digestive tract, and we propose to study the circadian rhythms of the Chinook salmon intestine to helpYIAL optimize salmon production. To do this we will first test different strains and stages of Chinook salmonfor digestive activity, to find at what time of day digestion is highest, and which stocks have the highestdigestive tract efficiency. These experiments will enable feedings and stocks to be aligned with the optimaltime of nutrient uptake, thus reducing feed cost and waste. Our project will specifically concern Chinooksalmon for the benefit of YIAL, however, our work will be easily transferable to benefit many otheraquaculture producers in Canada.