Critical need for cryostat to support research in behavioural neuroscience

这个应用程序是一个低温恒温器，需要有效和精确的组织切片，用于四个独立但相互关联的研究项目在达尔豪斯大学的心理和神经科学系。所要求的设备对于非常薄和可靠的大脑切片是必不可少的，这样蛋白质，基因和表观遗传标记的水平变化就可以定位和测量模式生物，如大鼠，小鼠和鸣禽。研究这些变化可以深入了解环境事件与大脑变化之间的因果关系，这些变化支持诸如压力反应，歌曲学习，社会行为等行为。检查脑组织切片的结果将提供对神经可塑性过程和潜在行为的神经机制的深入了解，包括神经系统的行为障碍（例如，焦虑、抑郁、社交焦虑）。

This application is for a cryostat, required for efficient and precise sectioning of tissue used in four independent but interrelated research programs in the Department of Psychology and Neuroscience at Dalhousie University. The requested equipment is essential for sectioning brains very thinly and reliably so that changes in levels of proteins, genes, and epigenetic markers can be localized and measured in model organisms such as rats, mice, and songbirds. Studying these changes allows insight into the causal relationships between environmental events and brain changes that support behaviours such as stress responding, song learning, social behaviour. The results produced from examining the sectioned brain tissue will provide insight into the process of neuroplasticity and the neural mechanisms underlying behaviour, including behavioural disorders of the nervous system (e.g., anxiety, depression, social anxiety).