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Sex-dependent effects of early life stress on the development of the basolateral amygdala-prefrontal cortex circuit for fear conditioning

Sex-dependent effects of early life stress on the development of the basolateral amygdala-prefrontal cortex circuit for fear conditioning
早期生活压力对基底外侧杏仁核-前额叶皮层回路发育的性别依赖性影响，以调节恐惧
批准号：
388279
负责人：
Walker Claire-Dominique
金额：
$55.45万
依托单位：
CIUSSS de l'Ouest-de-l'Ile-de-Montral-Douglas Hospital
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-09-01 至 2023-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=388279&lang=en
关键词：
Development Of Projections Early Life Stress Electrophysiology Fear Conditioning Microglia Morphology Neonatal Amygdala Prefrontal Cortex Sex Steroid Receptors Sexual Dimorphism

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中文摘要
翻译
父母虐待或忽视形式的早期生活压力（ELS）对大脑发育有重大影响，并增加了对情绪和情感障碍等与压力相关的病理的脆弱性。早期应激对焦虑和抑郁的影响
英文摘要
Early life stress (ELS) in the form of parental abuse or neglect has a significant impact on brain development and increases vulnerability to stress-related pathologies such as mood and emotionality disorders. The effect of early stress on anxiety and dep
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