Enzymatic Nanocellulose for Antibiofilm Applications

依赖海洋的活动对加拿大经济作出了重大贡献。然而，微生物在潮湿表面上的积累和粘附，以及它们系统地组织成稳定、协调、有弹性的群落（生物膜），每年给加拿大海洋工业造成数十亿美元的设备损坏、能源损失和产品污染（生物污染）。因此，需要新的、有效的、环保的选择来控制污染。**BIOSA TECHNOLOGIES LTD是一家专业从事酶生物技术的公司。目前，BIOSA**TECHNOLOGIES LTD正在寻求将他们的适应性酶与先进的定制纳米材料相结合，用于制造用于船舶设备和装置的抗生物膜涂层。为了满足公司的需求，我们建议开发具有抗菌和防污性能的环保、无毒和工业可持续的酶修饰纳米纤维素。随着环境对可持续性和报废处理挑战的关注不断增加，我们建议从纤维素等可再生资源中提取的功能性“绿色”材料是解决**公司特定问题的可行和有效的解决方案，具有低维护和生命周期成本、稳定性、可重用性、基材和**产品特异性。**加拿大拥有世界上最长的海岸线和第四大海洋领土；海洋资源是我们最重要的资产之一。的确，在更好地利用加拿大海洋部门的科学技术**和建立创新的、以知识为基础的海洋经济方面存在着巨大的潜力。该项目采用化学、生物学和纳米技术的多学科方法，预计其成果不仅将通过发明一种全新、高效和可持续的生物纳米技术，为加拿大的卓越和竞争力做出贡献，而且还将创造具有巨大商业化潜力的加拿大知识产权。

Ocean-dependent activities make a substantial contribution to the Canadian economy. However, accumulation**and adhesion of microorganisms on wetted surfaces and their systematic organization into stable, coordinated,**resilient communities (biofilms) costs the Canadian marine industry billions of dollars each year in equipment**damage, energy losses and product contamination (biofouling). It follows that new, effective, and**environmentally compatible options are needed to control fouling.**BIOSA TECHNOLOGIES LTD is a company specializing in enzymatic biotechnology. Currently, BIOSA**TECHNOLOGIES LTD is looking to combine their adapted enzymes with advanced, customized**nanomaterials for the fabrication of anti-biofilm coatings for marine equipment and installations. To address**the company's need, we propose the development of environmentally benign, non-toxic and industrially**sustainable enzyme-modified nanocellulose with antimicrobial and antifouling properties. With environmental**concerns over sustainability and end-of-life disposal challenges on the rise, we suggest that functional 'green'**materials derived from renewable resources such as cellulose represent a viable and effective solution to the**company's specific problem, offering low maintenance and lifecycle costs, stability, reusability, substrate and**product specificity.**Canada has the longest coastline and the fourth largest ocean territory in the world; maritime resources are**one of our most significant assets. Indeed, enormous potential exists to better leverage science and technology**in Canada's ocean sectors and to build an innovative, knowledge-based ocean economy. The outcomes of this**project - which follows a multidisciplinary approach at the interface of chemistry, biology and nanotechnology**- are expected not only to contribute to Canadian excellence and competitiveness through the invention of a**completely novel, efficient and sustainable bionanotechnology, but also to lead to the creation of Canadian**intellectual property with great potential for commercialization.