Discovering the effects of DRD2 genotype-based variants on D2 receptor distribution in patients with Parkinson's disease: a [11C]-(+)-PHNO PET study
Discovering the effects of DRD2 genotype-based variants on D2 receptor distribution in patients with Parkinson's disease: a [11C]-(+)-PHNO PET study
批准号:
404111
负责人:
Valli Mikaeel
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-10-01 至 2021-10-01
中文摘要
帕金森氏病(PD)患者的心理功能和运动计划的潜在损害源于纹状体和前额叶皮质内的多巴胺能信号的丢失。这些脑区内的神经元含有两种多巴胺D2受体亚型-
英文摘要
The underlying impairment of mental functioning and motor planning in Parkinson's disease (PD) stems from the dopaminergic signal loss within the striatum and prefrontal cortex. Neurons within these brain regions contain two dopamine D2 receptor isoforms-
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Exploring D2 receptor isoforms with [11C]-(+)-PHNO Radiotracer
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批准号:368979
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项目类别:Studentship Programs
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资助金额:$1.27万
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财政年份:2016
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负责人:Valli Mikaeel
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依托单位:
海外基金