Structural characterization of candidate anti-mycobacterial antibiotics bound to the CIII2CIV2 respiratory supercomplex
Structural characterization of candidate anti-mycobacterial antibiotics bound to the CIII2CIV2 respiratory supercomplex
批准号:
397372
负责人:
Tan Yong Zi
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-11-01 至 2021-11-01
中文摘要
就像人类一样,分枝杆菌,如引起结核病和麻风病的物种,需要氧气才能生存。然而,允许分枝杆菌利用氧气的细胞系统与人类的同等系统有很大的不同。这一组合
英文摘要
Just like humans, mycobacteria, such as the species that cause tuberculosis (TB) and leprosy, need oxygen to live. However, the cellular systems that allow mycobacteria to use oxygen differ dramatically from the equivalent systems in humans. This combinat
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