Cellular responses to protein misfolding in a yeast model of aging
Cellular responses to protein misfolding in a yeast model of aging
批准号:
409228
负责人:
Lajoie Patrick
金额:
$45.98万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01
中文摘要
亨廷顿氏病(HD)是一种神经退行性疾病,每7,000名加拿大人中就有一人患有这种疾病。亨廷顿舞蹈症的发生是由于亨廷顿基因中CAG重复序列的扩增,这增加了多聚谷氨酰胺(polyQ)重复序列的数量和亨廷顿蛋白原的倾向。
英文摘要
Huntington's disease (HD) is neurodegenerative disease affecting one in every 7,000 Canadians. HD occurs due to expansion of CAG repeats in the Huntingtin gene, which increases the number of polyglutamine (polyQ) repeats and tendency of the Huntingtin pro
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A system approach to the regulation of the Candida albicans acetylome in drug resistance and pathogenicity
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批准号:494861
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2023
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负责人:Lajoie Patrick
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依托单位:
海外基金