The role of the lineage oncogene ASCL1 in treatment-induced neuroendocrine prostate cancer
The role of the lineage oncogene ASCL1 in treatment-induced neuroendocrine prostate cancer
批准号:
409458
负责人:
Zoubeidi Amina
金额:
$61.3万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01
中文摘要
前列腺癌依赖雄激素受体(AR)来生长和存活。利用这种固有的弱点,已经开发出了有效的药物来“关闭”AR并使癌细胞缺乏燃料。这些疗法被广泛应用于临床。
英文摘要
Prostate tumours are addicted to the androgen receptor (AR) for growth and survival. Capitalizing on this inherent weakness, potent drugs have been developed to "turn off" the AR and starve cancer cells of fuel. These therapies are widely used in the clin
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会议论文
Canada Research Chairs - Tier 1
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批准号:441804
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项目类别:
-
资助金额:$101.99万
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财政年份:2020
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负责人:Zoubeidi Amina
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依托单位:
Hormone therapy induces reprogramming to drive aggressive prostate cancer
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批准号:380656
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项目类别:Operating Grants
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资助金额:$48.76万
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财政年份:2018
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负责人:Zoubeidi Amina
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依托单位:
海外基金