Targeting neutrophil-exosome regulated changes in tissue stiffness as a promoter of breast cancer liver metastasis
Targeting neutrophil-exosome regulated changes in tissue stiffness as a promoter of breast cancer liver metastasis
批准号:
422060
负责人:
Moraes Christopher
金额:
$4.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-02-01 至 2022-02-01
中文摘要
组织硬度的增加以前被认为是原发和继发肿瘤中癌症转移的重要驱动因素。然而,癌症进展过程中组织僵硬的生物学机制仍不清楚。中性粒细胞有
英文摘要
Increased tissue stiffness has previously been implicated as an important driver of cancer metastasis in primary and secondary tumors. However, the biological mechanisms by which tissues stiffen during cancer progression remain unclear. Neutrophils have
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会议论文
Reconceptualizing cancer metastasis as a balance of intra-tumoural mechanical forces
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批准号:388210
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项目类别:Operating Grants
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资助金额:$4.52万
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财政年份:2018
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负责人:Moraes Christopher
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依托单位:
Respiratory airway injury arising from rupture of occluding liquid plugs: identifying physical mechanisms causing idiopathic pulmonary fibrosis
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批准号:256083
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项目类别:Fellowship Programs
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资助金额:$3.64万
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财政年份:2012
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负责人:Moraes Christopher
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依托单位:
海外基金