Does inflammation in brain cause hypoxia, which then exacerbates inflammation: a multimodal study using the EAE inflammation model of multiple sclerosis.
Does inflammation in brain cause hypoxia, which then exacerbates inflammation: a multimodal study using the EAE inflammation model of multiple sclerosis.
批准号:
418793
负责人:
Dunn Jeff F
金额:
$62.42万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01
中文摘要
我们发现,许多多发性硬化症患者的大脑含氧量较低(缺氧)。我们还在小鼠EAE模型中发现了脑缺氧,这是最常用的中枢神经系统炎症的动物模型。这支持了BOT的想法
英文摘要
We have discovered that many people with MS have low oxygen levels in the brain (hypoxia). We have also found brain hypoxia in the mouse EAE model, the most commonly used animal model of central nervous system inflammation. This supports the idea that bot
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