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Sex as a Biological Variable Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses

Sex as a Biological Variable Supplement - Understand the high pathogenicity and zoonotic transmission of the COVID-19 virus: evasion of host innate immune responses
性别作为生物变量补充 - 了解 COVID-19 病毒的高致病性和人畜共患传播：逃避宿主先天免疫反应
批准号：
424691
负责人：
Liang Chen
金额：
$3.64万
依托单位：
Lady Davis Institute for Medical Research (Mtl)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-04-01 至 2021-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=424691&lang=en
关键词：
Covid-19. Innate Immune Response Interferon Sars-Cov Viral Pathogenicity Zoonotic Transmission

项目摘要

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中文摘要
翻译
冠状病毒对人类来说并不新鲜。人类冠状病毒OC43和229E早在20世纪60年代就被发现。这两种病毒都会引起普通感冒，这是一种轻微的上呼吸道感染。然而，当2002年SARS带来时，情况开始发生变化
英文摘要
Coronaviruses are not new to humans. The human coronaviruses OC43 and 229E were discovered as early as in the 1960s. Both viruses cause common cold, a mild infection of our upper respiratory tract. However, the story started to change in 2002 when SARS br
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Investigate the immune modulation function of SARS-CoV-2 accessory protein ORF8
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