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Rational Design and Characterization of a Conformationally Stabilized Next-Generation Immunogen Against Malaria

Rational Design and Characterization of a Conformationally Stabilized Next-Generation Immunogen Against Malaria
构象稳定的下一代抗疟疾免疫原的合理设计和表征
批准号:
437188
负责人:
Thai Elaine
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-11-01 至 2023-11-01

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中文摘要
翻译
疟疾是一个全球性的健康问题,对目前干预措施的抵抗力不断增加,加大了对强效疫苗的需求。靶向环子孢子蛋白(CSP)的抗体(Abs),CSP是一种覆盖疟疾寄生虫表面的蛋白质,介导
英文摘要
Malaria is a global health concern and increasing resistance to current interventions has amplified the need for a potent vaccine. Antibodies (Abs) targeting circumsporozoite protein (CSP), a protein coating the surface of malaria parasites that mediates
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Rational Design and Characterization of a Conformationally Stabilized Next-Generation Immunogen Against Malaria
  • 批准号:
    440100
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $7.65万
  • 财政年份:
    2020
  • 负责人:
    Thai Elaine
  • 依托单位:
Structure-Based Design of Ubiquitin-Specific Protease 18 Inhibitors
  • 批准号:
    406463
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2018
  • 负责人:
    Thai Elaine
  • 依托单位:
海外基金