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Structure-Based Design of Ubiquitin-Specific Protease 18 Inhibitors

Structure-Based Design of Ubiquitin-Specific Protease 18 Inhibitors
基于结构的泛素特异性蛋白酶 18 抑制剂的设计
批准号：
406463
负责人：
Thai Elaine
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-12-01 至 2019-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406463&lang=en
关键词：
Antiviral Binding Interactions Biochemistry High Resolution Modelling Studies Protease Inhibition Protein Biology Protein Structure Therapeutic Development X-Ray Crystallography

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中文摘要
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英文摘要
During a viral infection such as the flu, viruses invade the host organism’s cells and hijack their resources to generate new viral particles, which go on to infect other cells within the host. However, if a cellular protein known as interferon-stimulated
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Rational Design and Characterization of a Conformationally Stabilized Next-Generation Immunogen Against Malaria
  • 批准号：
    440100
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2020
  • 负责人：
    Thai Elaine
  • 依托单位：
    Hospital for Sick Children (Toronto)
Rational Design and Characterization of a Conformationally Stabilized Next-Generation Immunogen Against Malaria
  • 批准号：
    437188
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2020
  • 负责人：
    Thai Elaine
  • 依托单位：
    University of Toronto
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