Structural dynamics of nucleosome core particles upon DNA methylation and MeCP2 binding
Structural dynamics of nucleosome core particles upon DNA methylation and MeCP2 binding
批准号:
441129
负责人:
Bolik-Coulon Nicolas
金额:
$9.83万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2023-12-01
中文摘要
在人类中,DNA被组织成基本单位,它被包裹在蛋白质核心周围,形成一种称为核小体核心颗粒(NCP)的结构。ncp会受到各种化学修饰,影响它们的DNA和蛋白质成分,
英文摘要
In humans DNA is organized into basic units in which it is wrapped around a protein core to form a structure called a nucleosome core particle (NCP). NCPs are subject to a variety of chemical modifications, affecting both their DNA and protein components,
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