Mass spec studio: business intelligence software for the international laboratory industry (a Phase IIb project)
Mass spec studio: business intelligence software for the international laboratory industry (a Phase IIb project)
批准号:
557341-2020
负责人:
Schriemer, David
金额:
$10.6万
依托单位:
依托单位国家:
加拿大
项目类别:
Idea to Innovation
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-01-01 至 2021-12-31
中文摘要
许多慢性人类疾病仍然得不到很好的治疗。癌症、关节炎、胃肠道疾病、肾脏疾病等许多疾病缺乏有效的治疗方法。开发治疗这些疾病的药物,提高社会的健康水平,是现代医学的目标。这项工作涉及疾病性质的基础研究、药物产品的发现和开发以及药物监测。所有这些活动涉及多个行业,严重依赖分子分析的科学工具,如质谱仪。这些工具被用来发现药物,缩短药物开发的道路,确保产品安全,并确定药物是否在人群中起作用。质谱仪和许多现代分析工具一样,会产生难以解释的复杂数据流。目前的项目将推出一个名为质量谱工作室的强大开发框架,以创建数据分析软件产品。这个专有框架是一个支持质谱学的应用程序开发生成器,可以扩展到其他技术。该项目将提供其旗舰产品(HXaut),用于测量生物制剂的安全性和稳定性,这是一种重要的新药物治疗类别。HXAUTO的成功商业化将验证我们的商业计划,并导致与一家大型国际生命科学公司合作成立一家新的加拿大软件设计公司。
英文摘要
Many chronic human conditions remain poorly treated. Diseases like cancer, arthritis, gastrointestinal disorders, kidney disease and many others lack effective therapies. It is the goal of modern medicine to develop drugs for these diseases and improve the health-span of society. The effort involves fundamental research into the nature of disease, drug product discovery and development, and drug monitoring. All these activities stretch over multiple industries and rely heavily upon scientific tools of molecular analysis, like the mass spectrometer. These tools are used to discover drugs, shorten the path to their development, ensure product safety and determine if the drugs are working in the population. Mass spectrometers, like many modern tools of analysis, generate complex data streams that are difficult to interpret. The current project will launch a powerful development framework called the Mass Spec Studio to create software products for data analytics. This proprietary framework is an app development generator that supports mass spectrometry and can be expanded to other techniques. The project will deliver its flagship product (HXauto) for measuring the safety and stability of biologics, an important new class of drug therapy. Successful commercialization of HXauto will validate our business plans and lead to a new Canadian software design firm in partnership with a major international life sciences company.
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Mass spec studio: business intelligence software for the international laboratory industry (a Phase IIb project)
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批准号:557341-2020
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项目类别:Idea to Innovation
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资助金额:$7.73万
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财政年份:2021
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:RGPIN-2017-04879
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项目类别:Discovery Grants Program - Individual
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资助金额:$18.07万
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财政年份:2021
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负责人:Schriemer, David
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依托单位:
NanoLC System for Ultrasensitive Hydrogen/Deuterium Exchange Mass Spectrometry
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批准号:RTI-2021-00200
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项目类别:Research Tools and Instruments
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资助金额:$10.57万
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财政年份:2020
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:RGPIN-2017-04879
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项目类别:Discovery Grants Program - Individual
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资助金额:$9.03万
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财政年份:2020
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:507841-2017
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2019
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:RGPIN-2017-04879
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项目类别:Discovery Grants Program - Individual
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资助金额:$9.03万
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财政年份:2019
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:507841-2017
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2018
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:RGPIN-2017-04879
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项目类别:Discovery Grants Program - Individual
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资助金额:$9.03万
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财政年份:2018
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负责人:Schriemer, David
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依托单位:
Characterizing complex protein states with next generation HX-MS concepts
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批准号:486813-2015
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项目类别:Collaborative Research and Development Grants
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资助金额:$8.59万
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财政年份:2018
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负责人:Schriemer, David
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依托单位:
Mass spec studio software for the pharmaceutical market - a phase one project
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批准号:508445-2017
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项目类别:Idea to Innovation
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资助金额:$9.11万
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财政年份:2017
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:RGPIN-2017-04879
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项目类别:Discovery Grants Program - Individual
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资助金额:$9.03万
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财政年份:2017
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负责人:Schriemer, David
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依托单位:
Proteomics systems for integrative structural biology
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批准号:507841-2017
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2017
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负责人:Schriemer, David
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依托单位:
Characterizing complex protein states with next generation HX-MS concepts
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批准号:486813-2015
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项目类别:Collaborative Research and Development Grants
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资助金额:$10.5万
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财政年份:2017
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负责人:Schriemer, David
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依托单位:
Characterizing complex protein states with next generation HX-MS concepts
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批准号:486813-2015
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项目类别:Collaborative Research and Development Grants
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资助金额:$7.63万
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财政年份:2016
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负责人:Schriemer, David
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依托单位:
Structural Mass Spectometry for protein modeling
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批准号:298351-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2016
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负责人:Schriemer, David
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依托单位:
Role of Immunoglobulin Light Chain Derived Peptides in Preventing Multiple Myeloma Associated Cast Nephropathy
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批准号:487164-2015
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项目类别:Engage Grants Program
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资助金额:$1.82万
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财政年份:2015
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负责人:Schriemer, David
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依托单位:
Structural Mass Spectometry for protein modeling
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批准号:298351-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2015
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负责人:Schriemer, David
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依托单位:
Structural Mass Spectometry for protein modeling
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批准号:298351-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2014
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负责人:Schriemer, David
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依托单位:
Structural Mass Spectometry for protein modeling
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批准号:298351-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2013
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负责人:Schriemer, David
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依托单位:
Structural Mass Spectometry for protein modeling
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批准号:298351-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.64万
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财政年份:2012
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负责人:Schriemer, David
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依托单位:
国内基金
海外基金
大棚膜下滴灌及其生态环境的SPEC调控效应研究
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批准号:50979077
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项目类别:面上项目
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资助金额:33.0万元
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批准年份:2009
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负责人:罗金耀
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依托单位: