The functional role of Gli transcription factors in adult hematopoiesis and leukemic transformation.
The functional role of Gli transcription factors in adult hematopoiesis and leukemic transformation.
批准号:
195820
负责人:
Maedler-Kron Chelsea R
金额:
$4.81万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-10-01 至 2012-10-01
中文摘要
成人血细胞的发育,称为造血,取决于关键的信号通路。这些途径,即刺猬途径,涉及许多不同因素的相互作用,以指导造血干细胞成熟或保持休眠。
英文摘要
The development of adult blood cells, known as hematopoiesis, is dependent on key signaling pathways. These pathways, namely the Hedgehog pathway, involve the interaction of many different factors to guide a blood stem cell to maturity or to remain dorman
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