Determining Donor-Specific Antibody Pathogenicity in Kidney Transplantation Using Tissue Proteomics and Systems Immunology
Determining Donor-Specific Antibody Pathogenicity in Kidney Transplantation Using Tissue Proteomics and Systems Immunology
批准号:
451989
负责人:
Konvalinka Ana
金额:
$65.48万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
目的:肾移植是治疗终末期肾病的最佳方法。然而,大多数肾脏都会过早衰竭。移植物过早丢失的主要原因是抗体介导的排斥反应(Amr),这种排斥反应是由针对供者的抗体引起的。
英文摘要
PURPOSE: Kidney transplantation is the best treatment for end stage kidney disease. However, most kidneys fail prematurely. The main cause of premature graft loss is antibody mediated rejection (AMR), which is caused by antibodies against the donor that a
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会议论文
Health Research Presentations Centered on Engineering and Allocating Better Grafts: Hosted by the Canadian Donation and Transplantation Research Program
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批准号:485606
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项目类别:Miscellaneous Programs
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资助金额:$0.58万
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财政年份:2023
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负责人:Konvalinka Ana
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依托单位:
The Impact of Sex on Kidney Metabolism. Implications for Diabetic Kidney Disease
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批准号:377950
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项目类别:Operating Grants
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资助金额:$10.93万
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财政年份:2017
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负责人:Konvalinka Ana
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依托单位:
Systems Biology Approaches to Decipher Novel Mechanisms and Markers of Antibody Mediated Rejection in Kidney Transplantation
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批准号:350627
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项目类别:Salary Programs
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资助金额:$6.65万
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财政年份:2016
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负责人:Konvalinka Ana
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依托单位:
海外基金