Mer receptor tyrosine kinase in human macrophages mediates the clearance of apoptotic cells by modulating the activity of axß2 integrins and Rab17
Mer receptor tyrosine kinase in human macrophages mediates the clearance of apoptotic cells by modulating the activity of axß2 integrins and Rab17
批准号:
466569
负责人:
Dickson Brandon H
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-12-01 至 2022-12-01
中文摘要
死亡的细胞必须被称为巨噬细胞的免疫细胞清除。巨噬细胞在将细胞内化到被称为胞浆体的膜囊中之前,使用诸如Mer受体酪氨酸激酶(MerTK)的受体来识别垂死细胞,
英文摘要
Dying cells must be cleared by immune cells called macrophages. Macrophages recognize dying cells using receptors such as Mer receptor tyrosine kinase (MerTK) before internalizing cells into membranous sacs called efferosomes, where the cells are eventual
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