Real-time compliance monitoring system for digital therapies and diagnostics

用于数字治疗和诊断的真实的实时依从性监测系统提供了一种用于监测患者对数字治疗（例如，常见视觉障碍弱视的治疗）的依从性的新颖方法，该方法考虑了许多参数，诸如眼睛注视、眨眼、头部姿势、面部表情、相对眼睛稳定性和打哈欠。它能够检测患者是否佩戴治疗所需的3D眼镜和/或治疗期间的眼科处方。它可以检测患者是否正在执行治疗或其他人（例如兄弟姐妹）。它还实时检测七种情绪，即：“快乐”，“悲伤”，“厌恶”，“中性”，“愤怒”，“惊讶”和“害怕”。这种创新的一些优点包括：（1）能够实时跟踪多个参数。(2)产生反馈信号，以重新获得患者对治疗的注意力，或者在检测到患者心烦意乱或心不在焉时提醒他们的父母/护理人员/临床医生。(3)监控患者依从性并提供详细的依从性分析。这项创新在患者和驾驶员监控行业以及视力（如弱视）和精神疾病（如ADHD）的治疗中有应用。数字患者监测设备在治疗各种疾病方面越来越受欢迎，特别是在COVID-19的背景下。虽然技术进步，自动驾驶汽车的普及和车祸的增加使得驾驶员监控系统对汽车行业非常有价值。作为该市场评估赠款的一部分，选定的顾问（Adventus）将进行全面的市场分析，以确定最合适的市场机会，沿着与特定细分市场中技术应用相关的技术，营销和财务挑战。有利的市场评估结果将1）制定商业化战略，并有助于吸引潜在的许可证持有者2）为提交后续NSERC I2 I第1阶段项目提案奠定基础。

The Real Time Adherence Monitoring System for Digital Therapies and Diagnostics provides a novel approach for monitoring a patient's compliance to digital therapies (e.g. treatment of the common vision disorder amblyopia) that takes into account many parameters such as eye gaze, eye blinking, head pose, facial expression, relative eye stability and yawning. It is able to detect whether a patient is wearing the 3D glasses required for treatment and/or ophthalmic prescription during therapy. It can detect whether the patient is performing the therapy or someone else (e.g. a sibling). It also detects seven emotions in real-time, namely: "Happy", "Sad", "Disgust", "Neutral", "Anger", "Surprise" and "Scared". Some advantages of this innovation include: (1) ability to track multiple parameters in real-time. (2) produce feedback signals to regain patient's attention to treatment or alert their parent/caregiver/clinician upon detecting that the patient is upset or unengaged. (3) monitor patient adherence and provide detailed adherence analytics. This innovation has applications in the patient and driver monitoring industries as well as the treatment of vision (e.g. amblyopia) and psychiatric disorders (e.g. ADHD). Digital patient monitoring devices are becoming increasing popular for the treatment of a wide range of disorders, particularly within the context of COVID-19. While technological advancements, prevalence of autonomous vehicles and rise in car accidents have made driver monitoring systems highly valuable for the automotive industry. As part of this Market Assessment grant, the selected consultant (Adventus) will perform a thorough market analysis to identify the most suitable market opportunities along with technical, marketing and financial challenges associated with the application of the technology in a particular market segment. A favorable market assessment result will 1) formulate the commercialization strategy and help attract potential licensees 2) form the basis for submitting a follow-on NSERC I2I Phase 1 project proposal.