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Exploring the therapeutic potential of combined inhibition of MNK1/2 and CDK4/6 to treat melanoma.

Exploring the therapeutic potential of combined inhibition of MNK1/2 and CDK4/6 to treat melanoma.
探索联合抑制 MNK1/2 和 CDK4/6 治疗黑色素瘤的治疗潜力。
批准号:
461155
负责人:
Miller Wilson H
金额:
$61.3万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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中文摘要
翻译
激活免疫系统的药物对越来越多的致命恶性肿瘤的反应和总体生存率有了显著的改善。不幸的是,这些疗法并不是对所有患者都有效。我们已经研究了小分子
英文摘要
Drugs that activate the immune system have provided dramatic improvements in response and overall survival to a growing number of deadly malignancies. Unfortunately, these therapies do not work in all patients. We have studied how small molecules that inh
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