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Elucidating the mitotic mechanisms that are needed for alveologenesis in the pregnant mammary gland and are likely to be disturbed in pregnancy-associated breast cancer.

Elucidating the mitotic mechanisms that are needed for alveologenesis in the pregnant mammary gland and are likely to be disturbed in pregnancy-associated breast cancer.
阐明怀孕乳腺中肺泡发生所需的有丝分裂机制，并且可能在妊娠相关乳腺癌中受到干扰。
批准号：
472385
负责人：
Maxwell Christopher A
金额：
$7.29万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-09-01 至 2023-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472385&lang=en
关键词：
Alveologenesis Asymmetric Cell Division Brca1 Cytokinesis Hereditary Breast Cancer Involution Mitosis Oriented Cell Division Pregnancy-Associated Breast Cancer

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中文摘要
翻译
妊娠相关的乳腺癌总体上是罕见的，加拿大每年约有120例。但是，对于30岁以下患乳腺癌的加拿大妇女来说，至少五分之一的人会在怀孕期间或接下来的一年中患上乳腺癌。
英文摘要
Pregnancy-associated breast cancer is rare overall with about 120 cases each year in Canada. But, for Canadian women that develop breast cancer under the age of 30, at least one in five will develop breast cancer during pregnancy or in the following one y
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Mechanisms that impact the cell division axis and phenotype for BRCA1-mutant mammary epithelial cells.
Control of cell division by RHAMM in child development and human health
  • 批准号：
    301858
  • 项目类别：
    Salary Programs
  • 资助金额：
    $21.86万
  • 财政年份：
    2013
  • 负责人：
    Maxwell Christopher A
  • 依托单位：
    University of British Columbia
Understanding the mitotic and non-mitotic roles of RHAMM, a novel regulator for aurora kinase A.
Targeting aurora kinase A in paediatric sarcomas
  • 批准号：
    205746
  • 项目类别：
    Operating Grants
  • 资助金额：
    $0.0万
  • 财政年份：
    2010
  • 负责人：
    Maxwell Christopher A
  • 依托单位：
    University of British Columbia
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