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Genome targeting by highly accurate design of Zinc Fingers to enable novel therapeutics and research tools

Genome targeting by highly accurate design of Zinc Fingers to enable novel therapeutics and research tools
通过高度精确的锌指设计进行基因组靶向,以实现新型疗法和研究工具
批准号:
477283
负责人:
Kim Philip M
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-10-01 至 2023-10-01

项目摘要

项目成果

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中文摘要
翻译
像CRISPR这样的工具引领了生物医学科学的一场革命。它的主要优点是它可以轻松地瞄准基因组中的给定位置,然后切割或修改它。另一方面,它在应用上有根本的缺点
英文摘要
Tools like CRISPR have led a revolution in biomedical science. Its main advantage is the ease with which it can target a given location in the genome and either cut or otherwise modify it. On the other hand, it has fundamental disadvantages for applicatio
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Genome targeting by highly accurate design of Zinc Fingers to enable novel therapeutics and research tools
  • 批准号:
    479699
  • 项目类别:
    Operating Grants
  • 资助金额:
    $74.4万
  • 财政年份:
    2023
  • 负责人:
    Kim Philip M
  • 依托单位:
An integrated strategy for the development of next generation peptide therapeutics
  • 批准号:
    402426
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.22万
  • 财政年份:
    2019
  • 负责人:
    Kim Philip M
  • 依托单位:
A general strategy to develop inhibitors for transcription factors
  • 批准号:
    380690
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.65万
  • 财政年份:
    2018
  • 负责人:
    Kim Philip M
  • 依托单位:
A systematic strategy to develop inhibitors of protein-protein interactions as potential therapeutics
  • 批准号:
    357149
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.37万
  • 财政年份:
    2016
  • 负责人:
    Kim Philip M
  • 依托单位:
海外基金