NSERC CREATE Training Program for Controlled Release Leaders (ContRoL)

控释技术是指将生物活性物质（如药物、农药或营养物）与一种能够在适当时间内以适当剂量释放生物活性物质的材料相结合的技术，它已经给多个行业带来了革命性的变化。自20世纪50年代以来，医药和农业中的控释产品已被商业化使用；然而，我们制造先进材料的能力的最新发展，了解如何克服传统上限制有效生物活性递送的各种生物障碍，以及使用加速设计策略（例如统计，机器学习和高含量筛选）来快速优化特定应用的材料，共同为设计下一代控制释放载体提供了巨大的潜力。然而，控释专业人员通常在三个传统学科（制药科学、化学/生物医学工程或健康科学）中的一个进行培训，这些学科无法提供开发这种新的多样化知识库所需的综合培训基础。NSERC CREATE控制释放领导者（ContRoL）培训计划旨在通过建立一个世界领先的培训计划，专注于下一代控制释放车辆的集成和加速开发，以吸引和培养具有广泛基础的优秀HQP。通过设计思维和以领导力为重点的课程、实验室交流、行业经验、行业技能开发和就业准备研讨会、创业在线模块、多种科学交流模式的实践经验，以及与该领域领先的加拿大非营利组织（加拿大控制释放协会分会）的独特整合，ContRoL将为各级受训人员提供技术和跨学科技能基础，以满足对该领域专业人员的高需求。该项目的学员将致力于使患者治疗更安全、更有效，促进精准农业以确保粮食安全，创造预防疾病的功能性食品，以及设计用于长期疾病管理的生物医学设备。

Controlled release technology, the combination of a bioactive agent (e.g. a drug, pesticide, or nutrient) with a material that enables the bioactive to be delivered at the right dose over the right period of time, has revolutionized multiple industries. Controlled release products in medicine and agriculture have been used commercially since the 1950s; however, recent developments in our ability to fabricate advanced materials, to understand how to overcome various biological barriers that traditionally limit effective bioactive delivery, and to use accelerated design strategies (e.g. statistics, machine learning, and high-content screening) to rapidly optimize materials for specific applications collectively offer tremendous potential for designing next-generation controlled release vehicles. However, controlled release professionals are typically trained in one of three traditional disciplines (pharmaceutical sciences, chemical/biomedical engineering, or health sciences) that fail to give the comprehensive training foundation required to exploit this new diverse knowledge base. The NSERC CREATE Training Program for Controlled Release Leaders (ContRoL) aims to attract and train outstanding HQP with this broad-based perspective by establishing a world-leading training program focused on the integrated and accelerated development of next-generation controlled release vehicles. Through a mix of design thinking and leadership-focused courses, lab exchanges, industry experiences, workshops in industry-ready skills development and job readiness, entrepreneurship online modules, practical experience in multiple modes of scientific communication, and a unique integration with the leading Canadian non-profit organizations in the field (the Canadian Chapter of the Controlled Release Society), ContRoL will provide trainees at all levels with the technical and interdisciplinary skill foundation for meeting the high demand for professionals in this field. Trainees from this program will lead efforts to make patient therapeutics safer and more effective, facilitate precision agriculture to ensure food security, create functional foods for preventing disease, and design biomedical devices for long-term disease management.