Validating a biomarker and new potential therapy target in blood cancers
Validating a biomarker and new potential therapy target in blood cancers
批准号:
486438
负责人:
Gideon Alita M
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
肿瘤坏死因子受体(TNFR)在许多B细胞癌中呈结构性激活。反过来,这些受体招募肿瘤坏死因子受体相关因子蛋白(TRAF)来激活核因子kB(核因子kB),核因子kB是转录的大师
英文摘要
Tumor Necrosis Factor Receptors (TNFRs) become constitutively turned on in many instances of B cell cancers. In turn, these receptors recruit TNF Receptor Associated Factor Proteins (TRAFs) to activate Nuclear Factor-kB (NFkB), a master of transcription
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