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Development of a therapeutic single domain antibody to target the hepatitis B virus covalently closed circular DNA genome

Development of a therapeutic single domain antibody to target the hepatitis B virus covalently closed circular DNA genome
开发针对乙型肝炎病毒共价闭合环状 DNA 基因组的治疗性单域抗体
批准号:
475928
负责人:
D'souza Simmone
金额:
$7.65万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-11-01 至 2025-11-01

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中文摘要
翻译
尽管有有效的疫苗,但全世界有超过2.96亿人和25万加拿大人慢性感染乙型肝炎病毒(HBV)。乙型肝炎病毒专门针对肝细胞,并可引起持续的感染
英文摘要
Despite the availability of an effective vaccine, over 296 million people worldwide and 250,000 Canadians are chronically infected with the hepatitis B virus (HBV). The HBV specifically targets liver cells and can cause a persistent infection that can lea
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会议论文
Evaluating Hepatitis B Virus Covalently Closed Circular DNA Dynamics Within a Hepatitis Delta Virus Co-infection Model
  • 批准号:
    441196
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $0.44万
  • 财政年份:
    2020
  • 负责人:
    D'souza Simmone
  • 依托单位:
Targeting hepatitis B virus covalently closed circular DNA in vitro and in vivo
  • 批准号:
    428780
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2019
  • 负责人:
    D'souza Simmone
  • 依托单位:
海外基金