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Investigating the Consumption of Gut Metabolites by Crohn's Disease-Associated Escherichia Coli

Investigating the Consumption of Gut Metabolites by Crohn's Disease-Associated Escherichia Coli
研究克罗恩病相关大肠杆菌对肠道代谢物的消耗
批准号：
485920
负责人：
Mansour Sarah
金额：
$1.27万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-12-01 至 2023-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=485920&lang=en
关键词：
Adherent-Invasive Escherichia Coli Crohn'S Disease Evolution Gene Regulation Inflammation Inflammatory Bowel Disease Metabolic Adaptation Metabolism Short Chain Fatty Acids Trade-Off

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中文摘要
翻译
克罗恩病(CD)是一种由肠道细菌引起的炎症性肠道疾病，患者是遗传易感人群。粘附性侵袭性大肠埃希氏菌(AIEC)因其促炎特性而被公认为CD的危险因素。按事件
英文摘要
Crohn's disease (CD) is an inflammatory bowel disease driven by gut bacteria in genetically susceptible individuals. Adherent invasive strains of Escherichia coli (AIEC) have been recognized as CD risk factors due to their pro-inflammatory traits. By evol
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