Impact of host responses on mpox pathogenesis and tecovirimat efficacy in the Collaborative Cross mouse model of genetic diversity
Impact of host responses on mpox pathogenesis and tecovirimat efficacy in the Collaborative Cross mouse model of genetic diversity
批准号:
481136
负责人:
Rasmussen Angela
金额:
$36.43万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-02-01 至 2025-02-01
中文摘要
宿主对感染的反应是疾病严重程度的关键决定因素。然而,决定猴痘(猴痘)病毒病结局的宿主反应在很大程度上是未知的。此外,尽管抗病毒疗法可以有效地治疗麻痘感染
英文摘要
The host response to infection is a critical determinant of disease severity. However, host responses that dictate the outcome of mpox (monkeypox) virus disease are largely unknown. Furthermore, although antiviral therapies can effectively treat mpox infe
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海外基金
Journal of Genetics and Genomics
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批准号:31224803
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项目类别:专项基金项目
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资助金额:24.0万元
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批准年份:2012
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负责人:于昕
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依托单位: