Cell of origin dependencies in pediatric high-grade gliomas
Cell of origin dependencies in pediatric high-grade gliomas
批准号:
480066
负责人:
Kleinman Claudia L
金额:
$86.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01
中文摘要
几种类型的非常侵袭性和致命性的儿童脑瘤起源于大脑发育过程。引发这种疾病的遗传事件发生在细胞分化的非常早期,通常是在出生之前。
我们的工作模式是逮捕
英文摘要
Several types of very aggressive and fatal pediatric brain tumors originate during brain development. The genetic event that triggers the disease happens very early during cellular differentiation and often before birth.
Our working model is that arrest
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会议论文
Modeling gene expression trajectories in the human developing brain: applications to pediatric brain tumors
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批准号:371012
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项目类别:Operating Grants
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资助金额:$54.89万
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财政年份:2017
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负责人:Kleinman Claudia L
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依托单位:
海外基金