Developing a multimodal imaging pipeline for antisense technology

反义分子代表着生命科学的革命性药物发现平台，但要了解它们在细胞和组织中的分布是具有挑战性的。通过整合纳米生物技术方法，该项目希望开发和应用创新的成像工作流程，以纳米级的精度跟踪细胞和组织中的反义分子。预期的结果包括对这些分子在细胞和组织之间运输的新知识，以及改进的成像方法。该项目将为特定的细胞和组织提供更具战略性的反义分子输送，这将为澳大利亚社区带来显著的下游经济和社会效益。

Antisense molecules represent a revolutionary drug discovery platform for life science, but to understand their distributions in cells and tissues is challenging. By integrating nanobiotechnology approaches, this project expects to develop and apply innovative imaging workflow to track antisense molecules in cells and tissues with nanoscale precision. Expected outcomes include new knowledge of the trafficking of these molecules across cells and tissues and refined imaging methods. This project should provide more strategic delivery of antisense molecules to specific cells and tissue, which will have significant downstream economic and social benefits to the Australian community.