Optimization of topical formulations for the treatment of basal cell carcinoma using the Feldan Shuttle technology

该ARD提案旨在验证用于治疗皮肤癌的新专利药物配方的效率。在本研究项目中，将使用临床前模型并进行验证，以证明该配方的功效及其与非配方治疗相比的优势。该项目将通过解决皮肤应用治疗方面的技术问题，大力支持支持合作伙伴，从而显著增强其产品组合，支持其经济增长和目标市场。此外，这些配方可能为基底细胞癌或遗传综合征（称为Gorlin综合征）患者提供显著改善，这些患者发生复发性肿瘤病变，导致需要进行系列手术或全身治疗，并产生不良反应。

This ARD proposal aims at validating the efficiency of new proprietary drug formulations for the treatment of skin cancers. In this research project, a preclinical model will be used and validated to demonstrate the efficacy of the formulation as well as its superiority compared to non-formulated treatment. This project will strongly support the supporting partner by addressing technical questions in the context of skin-applied treatments that will enhance significantly their portfolio to support their economic growth and target markets. Moreover, these formulations may provide significant improvement for patients having basal cell carcinoma or the genetic syndrome termed Gorlin Syndrome where recurrent tumoral lesions are occurring leading to problematic need for serial surgery or systemic treatment with adverse effects.