Uncovering Vulnerabilities of Alternative Telomere Maintenance Systems in Cancer
Uncovering Vulnerabilities of Alternative Telomere Maintenance Systems in Cancer
批准号:
488585
负责人:
Marchal Alexandre
金额:
$56.01万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01
中文摘要
端粒可以防止染色体逐渐缩短,这是一种与衰老有关的现象,但也与癌症等疾病有关。为了增殖,癌细胞通过各种构成潜能的途径延长其端粒
英文摘要
Telomeres protect against the gradual shortening of chromosomes, a phenomenon associated with aging but which is also relevant to diseases including cancer. To proliferate, cancer cells elongate their telomeres via various pathways that constitute potenti
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Ubiquitin-Dependent Regulation of DNA Replication during Stress
-
批准号:420960
-
项目类别:Operating Grants
-
资助金额:$55.73万
-
财政年份:2020
-
负责人:Marchal Alexandre
-
依托单位:
Roles of the PRP19 complex in the Maintenance of Genome Stability
-
批准号:356161
-
项目类别:Operating Grants
-
资助金额:$31.49万
-
财政年份:2016
-
负责人:Marchal Alexandre
-
依托单位:
海外基金