Understanding mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis
Understanding mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis
批准号:
487542
负责人:
Rubinstein John L
金额:
$86.94万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01
中文摘要
像人类一样,导致结核病(TB)的分枝杆菌使用氧气从营养物质中释放所需的能量。这一过程被称为氧化磷酸化,是最近批准的结核病药物和正在进行临床试验的药物的靶点
英文摘要
Like humans, the mycobacteria that cause tuberculosis (TB) use oxygen to release the energy they need from nutrients. This process is called oxidative phosphorylation and is targeted both by recently approved TB drugs and drugs undergoing clinical trials
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专著(0)
科研奖励(0)
会议论文
Canada Research Chair - Tier 1
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批准号:453863
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项目类别:
-
资助金额:$101.99万
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财政年份:2020
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负责人:Rubinstein John L
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依托单位:
Electron cryomicroscopy studies of eukaryotic rotary ATPases
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批准号:400606
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项目类别:Operating Grants
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资助金额:$69.38万
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财政年份:2019
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负责人:Rubinstein John L
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依托单位:
Structural analysis of mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis
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批准号:387707
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项目类别:Operating Grants
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资助金额:$69.38万
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财政年份:2018
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负责人:Rubinstein John L
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依托单位:
Cryo-EM analysis of the structure and dynamics of protein assemblies at energized membranes
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批准号:387628
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项目类别:Operating Grants
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资助金额:$152.07万
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财政年份:2018
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负责人:Rubinstein John L
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依托单位:
Electron cryomicroscopy of rotary ATPases
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批准号:303026
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项目类别:Operating Grants
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资助金额:$77.43万
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财政年份:2014
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负责人:Rubinstein John L
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依托单位:
CRC Tier 1
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批准号:314125
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项目类别:
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资助金额:$101.99万
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财政年份:2013
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负责人:Rubinstein John L
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依托单位:
Structural analysis of the ATP synthase and V-ATPase
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批准号:178548
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项目类别:Operating Grants
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资助金额:$42.84万
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财政年份:2009
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负责人:Rubinstein John L
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依托单位:
海外基金