Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics.
Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics.
复制标题
等离激元金桔梗的三相界面合成作为近红外光介导的声热治疗诊断学
DOI：
10.1021/ja503115n
复制
发表时间：
2014-06-11
影响因子：
15
通讯作者：
Chen, Xiaoyuan
中科院分区：
文献类型：
--
作者：
Huang, Peng;Rong, Pengfei;Lin, Jing;Li, Wanwan;Yan, Xuefeng;Zhang, Molly Gu;Nie, Liming;Niu, Gang;Lu, Jie;Wang, Wei;Chen, Xiaoyuan
提出了一种新型的具有多分支花瓣的金风铃草（GBF）平台，通过液-液-气三相界面系统制备，用于光声成像（派）引导的光热治疗（PTT）。在近红外（NIR）激光照射下，GBF具有很强的近红外吸收，在已报道的光热转换剂中表现出很强的PA响应和很高的光热转换效率（η = 74%）。派和PTT中的优异性能主要归因于GBF的独特特征：（i）具有增强的局部电磁场的多分支花瓣，（ii）诱导强等离子体激元耦合效应的相邻花瓣之间的狭长间隙，以及（iii）可以在声学传播期间有效地放大声学信号的钟形纳米结构。除了显著的PTT和优异的派效应之外，吸收NIR的GBF还可以应用于NIR光触发的药物递送、催化、表面增强的拉曼散射、隐身、拉曼、IR传感器、电信等。
We present a novel gold bellflower (GBF) platform with multiple-branched petals, prepared by a liquid–liquid–gas triphase interface system, for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Upon near-infrared (NIR) laser irradiation, the GBFs, with strong NIR absorption, showed very strong PA response and an ultrahigh photothermal conversion efficiency (η, ∼74%) among the reported photothermal conversion agents. The excellent performance in PAI and PTT is mainly attributed to the unique features of the GBFs: (i) multiple-branched petals with an enhanced local electromagnetic field, (ii) long narrow gaps between adjacent petals that induce a strong plasmonic coupling effect, and (iii) a bell-shaped nanostructure that can effectively amplify the acoustic signals during the acoustic propagation. Besides the notable PTT and an excellent PAI effect, the NIR-absorbing GBFs may also find applications in NIR light-triggered drug delivery, catalysis, surface enhanced Raman scattering, stealth, antireflection, IR sensors, telecommunications, and the like.
登录
查看更多内容
影响因子：
15
作者：
He, Jie;Huang, Xinglu;Nie, Zhihong
通讯作者：
Nie, Zhihong
叶酸共轭二氧化硅修饰的金纳米棒用于 X 射线/CT 成像引导的双模辐射和光热治疗
影响因子：
14
作者：
Huang, Peng;Bao, Le;Cui, Daxiang
通讯作者：
Cui, Daxiang
影响因子：
62.1
作者：
Kim, Chulhong;Favazza, Christopher;Wang, Lihong V.
通讯作者：
Wang, Lihong V.
影响因子：
17.1
作者：
Huang X;Peng X;Wang Y;Wang Y;Shin DM;El-Sayed MA;Nie S
通讯作者：
Nie S
影响因子：
16.1
作者：
Janib, Siti M.;Moses, Ara S.;MacKay, J. Andrew
通讯作者：
MacKay, J. Andrew