What can mice tell us about how vision works?
What can mice tell us about how vision works?
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DOI:
10.1016/j.tins.2011.07.002
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发表时间:
2011-09
影响因子:
15.9
通讯作者:
Niell, Cristopher M.
中科院分区:
文献类型:
--
作者:
Huberman, Andrew D.;Niell, Cristopher M.
Understanding the neural basis of visual perception is a longstanding fundamental goal of neuroscience. Historically, most vision studies were carried out on humans, macaque monkeys and cats. Over the last five years, however, a growing number of researchers have begun using mice to parse the mechanisms underlying visual processing- the rationale is that despite having relatively poor acuity, mice are unmatched in terms of the variety and sophistication of tools available to label, monitor and manipulate specific cell types and circuits. In this review, we discuss recent advances in understanding the mouse visual system at the anatomical, receptive field and perceptual level, focusing on the opportunities and constraints those features provide toward the goal of understanding how vision works.
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