Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas.

Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas.
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DOI:
10.1016/j.ijrobp.2008.08.070
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发表时间:
2009-07-01
影响因子:
7
通讯作者:
Kachnic, Lisa A.
Kachnic, Lisa A.
中科院分区:
医学1区
文献类型:
--
作者:
Myerson, Robert J.;Garofalo, Michael C.;El Naqa, Issam;Abrams, Ross A.;Apte, Aditya;Bosch, Walter R.;Das, Prajnan;Gunderson, Leonard L.;Hong, Theodore S.;Kim, J. J. John;Willett, Christopher G.;Kachnic, Lisa A.

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开发放射治疗肿瘤学组(RTOG)的选择性临床靶体积(CTV)定义图谱,用于计划肛门和直肠癌的盆腔调强放射治疗(IMRT)。RTOG的胃肠委员会成立了一个工作组(9名医生共同作者)来开发该图谱。他们回答了关于三个择期CTV的问卷(CTVA:髂内、骶前和直肠周围淋巴结区域,用于肛门和直肠病例计划; CTVB:髂外淋巴结区域,用于肛门病例计划和选定的直肠病例; CTVC:腹股沟淋巴结区域,用于肛门病例计划和选定的直肠病例),并在个体计算机断层扫描图像上概述这些区域。图像文件通过先进技术联盟共享。由共同作者之一(IEN)开发的程序利用二项式最大似然估计生成95%的组共识轮廓。计算机估计的共识轮廓,然后由小组审查和修改,以提供一个最终的轮廓共识图集。该小组达成了共识CTV定义,可用作直肠癌辅助治疗和肛门癌确定性治疗的指南。与妇科或泌尿生殖系统癌症的相似图谱最重要的区别是直肠系膜覆盖。详细的目标体积轮廓的指导方针和图像进行了讨论。本报告作为前瞻性RTOG试验的一部分,作为肛门和直肠癌调强放射治疗计划中选择性CTV定义的模板。
To develop a Radiation Therapy Oncology Group (RTOG) atlas of the elective clinical target volume (CTV) definitions to be used for planning pelvic intensity-modulated radiotherapy (IMRT) for anal and rectal cancers. The Gastrointestinal Committee of the RTOG established a task group (the nine physician co-authors) to develop this atlas. They responded to a questionnaire concerning three elective CTVs (CTVA: internal iliac, pre-sacral and peri-rectal nodal regions for both anal and rectal case planning; CTVB: external iliac nodal region for anal case planning and for selected rectal cases; CTVC: inguinal nodal region for anal case planning and for select rectal cases), and to outline these areas on individual computed tomography images. The imaging files were shared via the Advanced Technology Consortium. A program developed by one of the co-authors (IEN) utilized binomial maximum-likelihood estimates to generate a 95% group consensus contour. The computer-estimated consensus contours were then reviewed by the group and modified to provide a final contouring consensus atlas. The panel achieved consensus CTV definitions to be used as guidelines for the adjuvant therapy of rectal cancer and definitive therapy for anal cancer. The most important difference from similar atlases for gynecologic or genitourinary cancer is mesorectal coverage. Detailed target volume contouring guidelines and images are discussed. This report serves as a template for the definition of the elective CTVs to be used in IMRT planning for anal and rectal cancers, as part of prospective RTOG trials.
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发表时间: 2004-10-01
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影响因子: --
作者:
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通讯作者: Martinez, Alvaro