Incidence and clinical characteristics of childhood glaucoma: a population-based study.

Incidence and clinical characteristics of childhood glaucoma: a population-based study.
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DOI:
10.1001/archophthalmol.2010.41
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发表时间:
2010-04
影响因子:
--
通讯作者:
Mohney, Brian G.
Mohney, Brian G.
中科院分区:
其他
文献类型:
--
作者:
Aponte, Elisabeth P.;Diehl, Nancy;Mohney, Brian G.

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To describe the incidence and clinical characteristics of childhood glaucoma in a defined population of the United States. The medical records of all patients (< 20 years) meeting diagnostic criteria for glaucoma or glaucoma suspect, as residents of Olmsted County, Minnesota, from January 1, 1965, through December 31, 2004 were reviewed. Thirty children were diagnosed with glaucoma during the 40-year study period. The age- and sex-adjusted incidence of childhood glaucoma was 2.29 (95% CI: 1.47–3.12) per 100,000 residents < 20 years of age, with the following types and incidences: 19 acquired (1.46/100,000; 95% CI: 0.80–2.12), 6 secondary (0.45/100,000; 95% CI: 0.08–0.82) and 5 with primary glaucoma (0.38/100,000; 95% CI: 0.05–0.72). The birth prevalence of primary congenital glaucoma during the 40-year period was 1 in 68,254 births or 1.46 per 100,000 births (95% CI: 0.03–8.16). Twenty-four glaucoma suspects were also identified, yielding an incidence of 1.9 per 100,000 patients < 20 years of age (95% CI: 1.14–2.66). The incidence of childhood glaucoma in this population was 2.29 per 100,000 or 1 in 43,575 for patients <20 years of age. Acquired and secondary forms of glaucoma were the most common while congenital and juvenile glaucoma were rare.
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