Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing.
Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing.
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DOI：
10.1186/1471-2164-16-1
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发表时间：
2015-01-02
期刊：
影响因子：
4.4
通讯作者：
Kwon HW
中科院分区：
文献类型：
--
作者：
Park D;Jung JW;Choi BS;Jayakodi M;Lee J;Lim J;Yu Y;Choi YS;Lee ML;Park Y;Choi IY;Yang TJ;Edwards OR;Nah G;Kwon HW
蜜蜂是增加对与农业和基础科学相关的社会行为的分子和神经机制的理解的重要模型系统。西方蜜蜂（Apis mellifera）已被作为模式物种，其基因组序列已被公布。相比之下，亚洲蜜蜂（Apis cerana）的基因组尚未被测序。金凤花在亚洲国家已经种植了数千年，为养蜂业带来了可观的经济效益。与蜜蜂相比，蜜蜂具有不同的生物学特征，在维持东亚和南亚地区的生物多样性方面发挥了关键作用。本文报道了中国蜜蜂的首个全基因组序列。使用de novo组装方法，我们制作了a . cerana基因组的238 Mbp草图，并产生了10,651个基因。为了更好地了解这种蜜蜂的新特征，研究人员分析了蜜蜂的特异性基因。72%的中华绒螯蟹特异性基因具有一个以上的氧化石墨烯期，1696种酶被分类为125种途径。参与化学接受和免疫的基因被仔细鉴定，并与其他测序的昆虫模型进行了比较。其中包括10个味觉受体、119个气味受体、10个嗜离子受体和160个免疫相关基因。这是中国蜜蜂全基因组序列的首次报道，为比较社会基因组学提供了资源，特别是在昆虫社会性交流领域。这些重要的工具将有助于更好地理解亚洲蜜蜂的复杂行为和自然生物学，并预测其未来的进化轨迹。本文的在线版本（doi:10.1186/1471-2164-16-1）包含补充材料，可供授权用户使用。
The honey bee is an important model system for increasing understanding of molecular and neural mechanisms underlying social behaviors relevant to the agricultural industry and basic science. The western honey bee, Apis mellifera, has served as a model species, and its genome sequence has been published. In contrast, the genome of the Asian honey bee, Apis cerana, has not yet been sequenced. A. cerana has been raised in Asian countries for thousands of years and has brought considerable economic benefits to the apicultural industry. A cerana has divergent biological traits compared to A. mellifera and it has played a key role in maintaining biodiversity in eastern and southern Asia. Here we report the first whole genome sequence of A. cerana. Using de novo assembly methods, we produced a 238 Mbp draft of the A. cerana genome and generated 10,651 genes. A.cerana-specific genes were analyzed to better understand the novel characteristics of this honey bee species. Seventy-two percent of the A. cerana-specific genes had more than one GO term, and 1,696 enzymes were categorized into 125 pathways. Genes involved in chemoreception and immunity were carefully identified and compared to those from other sequenced insect models. These included 10 gustatory receptors, 119 odorant receptors, 10 ionotropic receptors, and 160 immune-related genes. This first report of the whole genome sequence of A. cerana provides resources for comparative sociogenomics, especially in the field of social insect communication. These important tools will contribute to a better understanding of the complex behaviors and natural biology of the Asian honey bee and to anticipate its future evolutionary trajectory. The online version of this article (doi:10.1186/1471-2164-16-1) contains supplementary material, which is available to authorized users.
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