Differential hippocampal and retrosplenial involvement in egocentric-updating, rotation, and allocentric processing during online spatial encoding: an fMRI study.
Differential hippocampal and retrosplenial involvement in egocentric-updating, rotation, and allocentric processing during online spatial encoding: an fMRI study.
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DOI：
10.3389/fnhum.2014.00150
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发表时间：
2014
影响因子：
2.9
通讯作者：
Baciu M
中科院分区：
文献类型：
--
作者：
Gomez A;Cerles M;Rousset S;Rémy C;Baciu M
新空间信息的编码方式似乎对解开空间记忆网络中决定性区域的作用至关重要（即，海马、海马旁、顶叶、压后、.）。几个数据来源汇集表明，海马并不总是参与或确实是必要的allocentric处理。海马参与空间编码可能反映了“在线”自我相关变化产生的新信息的整合。在这项fMRI研究中，参与者首先在虚拟现实环境中编码几个物体的位置，然后执行指向任务。Allocentric编码最大限度地利用调查的角度和对象到对象的指向任务。两个自我中心的编码条件，涉及自我相关的变化下处理的第一人称的角度来看，并涉及一个自我到对象指向任务。自我中心更新条件涉及导航，而自我中心与旋转条件只涉及方向的变化。空间编码条件的连接分析显示了广泛的激活枕顶额网络和几个中颞叶结构。有趣的是，与其他空间条件相比，只有楔区被非中心编码显著更多地招募。此外，在自我中心更新编码过程中发现海马激活增强，而在自我中心仅旋转条件下观察到压后激活。因此，在某些情况下，海马和压后结构-已知参与allocentric环境编码-表现出优先参与自我中心的空间编码。这些结果表明，在理解空间编码过程中所涉及的机制的复杂性方面，以非自我为中心的表征与以自我为中心的表征之间的原始区别似乎不再是足够的。
The way new spatial information is encoded seems to be crucial in disentangling the role of decisive regions within the spatial memory network (i.e., hippocampus, parahippocampal, parietal, retrosplenial,…). Several data sources converge to suggest that the hippocampus is not always involved or indeed necessary for allocentric processing. Hippocampal involvement in spatial coding could reflect the integration of new information generated by “online” self-related changes. In this fMRI study, the participants started by encoding several object locations in a virtual reality environment and then performed a pointing task. Allocentric encoding was maximized by using a survey perspective and an object-to-object pointing task. Two egocentric encoding conditions were used, involving self-related changes processed under a first-person perspective and implicating a self-to-object pointing task. The Egocentric-updating condition involved navigation whereas the Egocentric with rotation only condition involved orientation changes only. Conjunction analysis of spatial encoding conditions revealed a wide activation of the occipito-parieto-frontal network and several medio-temporal structures. Interestingly, only the cuneal areas were significantly more recruited by the allocentric encoding in comparison to other spatial conditions. Moreover, the enhancement of hippocampal activation was found during Egocentric-updating encoding whereas the retrosplenial activation was observed during the Egocentric with rotation only condition. Hence, in some circumstances, hippocampal and retrosplenial structures—known for being involved in allocentric environmental coding—demonstrate preferential involvement in the egocentric coding of space. These results indicate that the raw differentiation between allocentric versus egocentric representation seems to no longer be sufficient in understanding the complexity of the mechanisms involved during spatial encoding.
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影响因子：
1.7
作者：
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通讯作者：
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DOI：
10.1037/0278-7393.32.3.506
发表时间：
2006-05-01
影响因子：
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作者：
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通讯作者：
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