Complete Genome Sequence of Two Coxsackievirus A1 Strains That Were Cytotoxic to Human Rhabdomyosarcoma Cells

Complete Genome Sequence of Two Coxsackievirus A1 Strains That Were Cytotoxic to Human Rhabdomyosarcoma Cells
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对人横纹肌肉瘤细胞具有细胞毒性的两种柯萨奇病毒 A1 株的完整基因组序列

DOI:
10.1128/jvi.01567-12
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发表时间:
2012-08
期刊:
J. Virol
影响因子:
--
通讯作者:
Dongyan Wang
Dongyan Wang
中科院分区:
其他
文献类型:
--
作者:
Qiang Sun;Xiaolei Li;Huafang Jiang;Hongqiu An;Wenbo Xu;Yong Zhang;Shuangli Zhu;Hui Cui;Huifang Tian;Dongmei Yan;Guohong Huang;Zhen Zhu;Dongyan Wang

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ABSTRACT Coxsackievirus A1 (CVA1) belongs to human enterovirus species C within the family Picornaviridae, order Picornavirales. Two Chinese CVA1 isolates, HT-THLH02F/XJ/CHN/2011 and KS-ZPH01F/XJ/CHN/2011, were isolated from stool specimens of two healthy children in the Xinjiang Uygur autonomous region of China. They were found to elicit cytopathic effects in a human rhabdomyosarcoma cell line, and complete genome sequences of these two CVA1 isolates revealed that natural intertypic recombination events occurred between CVA1 and CVA22.
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