Comparing protein abundance and mRNA expression levels on a genomic scale.
Comparing protein abundance and mRNA expression levels on a genomic scale.
复制标题
比较基因组量表上蛋白质丰度和mRNA表达水平。
DOI:
10.1186/gb-2003-4-9-117
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发表时间:
2003
期刊:
影响因子:
12.3
通讯作者:
Gerstein M
中科院分区:
文献类型:
--
作者:
Greenbaum D;Colangelo C;Williams K;Gerstein M
We review the results of attempts to correlate protein abundance with mRNA expression levels, focusing on yeast. Attempts to correlate protein abundance with mRNA expression levels have had variable success. We review the results of these comparisons, focusing on yeast. In the process, we survey experimental techniques for determining protein abundance, principally two-dimensional gel electrophoresis and mass-spectrometry. We also merge many of the available yeast protein-abundance datasets, using the resulting larger 'meta-dataset' to find correlations between protein and mRNA expression, both globally and within smaller categories.
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通讯作者:
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10.1006/bbrc.2002.6678
发表时间:
2002-04-05
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3.1
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通讯作者:
Felschow, D