Task-dependent effects of interhemispheric inhibition on motor control.

Task-dependent effects of interhemispheric inhibition on motor control.
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DOI:
10.1016/j.bbr.2011.09.018
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发表时间:
2012-01-01
影响因子:
2.7
通讯作者:
Seidler, Rachael D.
Seidler, Rachael D.
中科院分区:
心理学3区
文献类型:
--
作者:
Fling, Brett W.;Seidler, Rachael D.

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大脑两半球间的交流是由易化和抑制的复杂平衡组成的,这种平衡是以任务依赖的方式调节的。然而,目前还不清楚如何在大脑半球间的相互作用的个体差异与运动性能。为了评估大脑半球间的抑制,我们利用同侧沉默期技术(iSP;由阈上经颅磁刺激诱发),这elevent抑制的意志运动活动。参与者执行三个力产生任务:1)单手(右手)恒定力,2)双手恒定力,(双手同时)和3)右手恒定力和左手正弦波跟踪的双手(双手独立)。我们发现,具有较大IHI能力的个体在单手右手收缩时表现出左手镜像EMG活动减少。然而,这些人表现出最差的性能在双手独立的生产力的任务。我们认为,高容量的IHI从一个运动皮层到另一个可以有效地防止“电机溢出”在unimanual任务,但它也可以限制在独立控制的双手任务的半球间的合作。
Interhemispheric communication consists of a complex balance of facilitation and inhibition that is modulated in a task-dependent manner. However, it remains unclear how individual differences in interhemispheric interactions relate to motor performance. To assess interhemispheric inhibition, we utilized the ipsilateral silent period technique (iSP; evoked by suprathreshold transcranial magnetic stimulation), which elicits inhibition of volitional motor activity. Participants performed three force production tasks: 1) unimanual (right hand) constant force, 2) bimanual constant force, (bimanual simultaneous) and 3) bimanual with right hand constant force and left hand sine wave tracking (bimanual independent). We found that individuals with greater IHI capacity demonstrated reduced mirror EMG activity in the left hand during unimanual right hand contraction. However, these same individuals demonstrated the poorest performance during the bimanual independent force production task. We suggest that a high capacity for IHI from one motor cortex to another can effectively prevent “motor overflow” during unimanual tasks, but it can also limit interhemispheric cooperation during independently controlled bimanual tasks.
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