CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis: the Framingham Heart Study.
CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis: the Framingham Heart Study.
复制标题
DOI:
10.1002/jmri.24239
复制
发表时间:
2014-04
影响因子:
4.4
通讯作者:
Manning, Warren J.
中科院分区:
文献类型:
--
作者:
Chuang, Michael L.;Gona, Philimon;Hautvast, Gilion L. T. F.;Salton, Carol J.;Breeuwer, Marcel;O'Donnell, Christopher J.;Manning, Warren J.
关键词:
To determine sex-specific reference values for left ventricular (LV) volumes, mass and ejection fraction (EF) in healthy adults using computer-aided analysis and to examine the effect of age on LV parameters. We examined data from 1494 members of the Framingham Heart Study Offspring cohort, obtained using short-axis stack cine SSFP CMR, identified a healthy reference group (without cardiovascular disease, hypertension, or LV wall motion abnormality) and determined sex-specific upper 95th percentile thresholds for LV volumes and mass, and lower 5th percentile thresholds for EF using computer-assisted border detection. In secondary analyses we stratified participants by age-decade and tested for linear trend across age groups. The reference group comprised 685 adults (423F; 61±9 years). Men had greater LV volumes and mass, before and after indexation to common measures of body size (all p<0.001). Women had greater EF (73±6 vs. 71±6%, p=0.0002). LV volumes decreased with greater age in both sexes, even after indexation. Indexed LV mass did not vary with age. LV EF and concentricity increased with greater age in both sexes. We present CMR-derived LV reference values. There are significant age and sex differences in LV volumes, EF and geometry, while mass differs between sexes but not age groups.
登录
查看更多内容
影响因子:
19.7
作者:
François, CJ;Fieno, DS;Finn, JP
通讯作者:
Finn, JP
影响因子:
5
作者:
Natori, Shunsuke;Lai, Shenghan;Bluemke, David A.
通讯作者:
Bluemke, David A.
影响因子:
6.4
作者:
Hudsmith, LE;Petersen, SE;Neubauer, S
通讯作者:
Neubauer, S
影响因子:
4.4
作者:
Codella, Noel C. F.;Cham, Matthew D.;Weinsaft, Jonathan W.
通讯作者:
Weinsaft, Jonathan W.
影响因子:
4.4
作者:
Corsi, Cristiana;Veronesi, Federico;Mor-Avi, Victor
通讯作者:
Mor-Avi, Victor